Fig. 1.

Relationship between the ln levels of M₁dG adducts per 10⁸ total nucleotides, expressed such as relative adduct labeling, and the ln levels of methylation, expressed such as percent 5-methylcytosine, at a specific CpG site, pos.1904864340, within the regulatory region of HIC1 in smokers after correction for age, gender, number of cigarettes/day, and percent neutrophils in differential blood counts. Abbreviations: HIC1, hypermethylated-in-cancer-1; M₁dG, malondialdehyde-deoxyguanosine