Table III.
Multivariable survival analysis by p14 ARF genotypes in 495 SCCOP patients
| p14 ARF genotypes | Total (495) | Events | Survival | ||||
|---|---|---|---|---|---|---|---|
| Death (all causes) | Death (owing to disease) | Recurrence | OS | DSS | DFS | ||
| aHR*, 95% CI | aHR, 95% CI | aHR, 95% CI | |||||
| p14 ARF-rs3731217 | |||||||
| TG+GG | 179 | 12 | 2 | 12 | 1.0 | 1.0 | 1.0 |
| TT | 316 | 62 | 33 | 47 | 6.7 (2.6–17.1) | 11.2 (2.5–50.6) | 2.6 (1.2–5.8) |
| p14 ARF-rs3088440 | |||||||
| GA+AA | 163 | 22 | 8 | 19 | 1.0 | 1.0 | 1.0 |
| GG | 332 | 52 | 27 | 40 | 1.2 (0.6–2.2) | 2.1 (0.8–5.4) | 1.8 (0.8–3.7) |
*Adjusted for age, sex, ethnicity, smoking, alcohol, T stage, N stage, treatment, comorbidity and tumor
HPV16 status in Cox’s models.