Table IV.
Multivariable survival analysis by p14 ARF genotypes in 397 tumor HPV16(+) SCCOP patients
| p14 ARF genotypes | Total (397) | Events | Survival | ||||
|---|---|---|---|---|---|---|---|
| Death (all causes) | Death (owing to disease) | Recurrence | OS | DSS | DFS | ||
| aHR*, 95% CI | aHR, 95% CI | aHR, 95% CI | |||||
| p14 ARF-rs3731217 | |||||||
| TG+GG | 157 | 12 | 2 | 11 | 1.0 | 1.0 | 1.0 |
| TT | 240 | 39 | 23 | 34 | 5.4 (2.0–14.6) | 10.1 (2.1–48.7) | 2.5 (1.0–5.9) |
| p14 ARF-rs3088440 | |||||||
| GA+AA | 144 | 17 | 7 | 17 | 1.0 | 1.0 | 1.0 |
| GG | 253 | 34 | 18 | 28 | 1.1 (0.6–2.3) | 1.6 (0.6–4.5) | 1.6 (0.7–3.6) |
*Adjusted for age, sex, ethnicity, smoking, alcohol, T stage, N stage, treatment, comorbidity and tumor
HPV16 status in Cox’s models