. 2013 Oct 31;35(1):69–75. doi: 10.1093/carcin/bgt339

Table III.

Statistically significant (P ≤ 0.05) haplotype × PAH interactions on B[a]P-DNA adducts in cord blood in Dominican participants

Maternal gene	SNP500Cancer SNP ID	Chromosome position	Reference haplotype	Variant haplotype	High PAH exposure with reference haplotype (n)	High PAH exposure with variant haplotype (n)	Interaction coefficient (β)^a	P
Maternal gene	SNP500Cancer SNP ID	Chromosome position	Reference haplotype	Variant haplotype	Low PAH Exposure with Reference Haplotype (n)	Low PAH Exposure with Variant Haplotype (n)	Interaction coefficient (β)^a	P
XRCC1	rs25487	44055726	G	A	65	19	−0.31	0.01
XRCC1	rs25489	44056412	G	G	66	21	−0.31	0.01
Newborn gene	SNP500Cancer SNP ID	Chromosome position	Reference haplotype	Variant haplotype	High PAH exposure with reference haplotype (n)	High PAH exposure with variant haplotype (n)	Interaction coefficient (β)^a	P
Newborn gene	SNP500Cancer SNP ID	Chromosome position	Reference haplotype	Variant haplotype	Low PAH exposure with reference haplotype (n)	Low PAH exposure with variant haplotype (n)	Interaction coefficient (β)^a	P
NQO1	rs10517	69743760	C	C	59	6	−0.51	0.03
	rs1800566	69745145	C	C	59	6
	rs689453	69752373	G	A	53	6
	rs689452	69752464	C	C	53	6

^aThe interaction coefficient (β) represents the increase or decrease in the effect of high PAH exposure on the log-transformed level of cord blood B[a]P-DNA adduct formation in the presence of the variant haplotype compared with the effect of high PAH exposure with the reference haplotype.