Table 1.
Conserved functions of let-7, bantam, and miR-279 in the nervous system.
| microRNA | Model organism | Function | Citation | |
|---|---|---|---|---|
| Development | let-7 | Drosophila | Maturation of neuromuscular junction (NMJ) | Caygill and Johnston (2008), Sokol et al. (2008) |
| Mushroom body (MB) differentiation | Kucherenko et al. (2012), Wu et al. (2012) | |||
| Human neural precursor cells embryonic stem cells | Pluripotency | Rybak et al. (2008), Cimadamore et al. (2013) | ||
| bantam | Drosophila | Glia cell growth in the brain and optic lobe | Reddy and Irvine (2011) | |
| Differentiation and number of glia cells in the opticlobe | Li and Padgett (2012) | |||
| miR-279 | Drosophila | CO2 neuron development | Cayirlioglu et al. (2008), Hartl et al. (2011) | |
| Regeneration | let-7 | C. elegans | AVM neuron axon regeneration | Zou et al. (2013) |
| Zebrafish | De-differentiation of Mueller glia cells | Ramachandran et al. (2010) | ||
| bantam | Drosophila | Dendritic aborisation (da) neuron regeneration | Song et al. (2012) | |
| Degeneration | let-7 | Mouse | Loss of cortical neurons through extracellular let-7 | Lehmann et al. (2012) |
| Behavior | miR-279 | Drosophila | Regulation of circadian rhythm | Luo and Sehgal (2012) |