Table 2.
HBV DNA load and infant HBV prophylaxis among 11 HBV transmitting mother-child pairs.
| Maternal HBV load (log10 IU/mL) |
Infant prophylaxis | Infant HBV load (log10 IU/mL) | |||||
|---|---|---|---|---|---|---|---|
| Pair | Maternal HBeAg |
Before delivery | Vaccination (months) |
HBIg | Birth – 10 days | 4 months | 6 months |
| 0387 | + | 7.84 | 0, 1, 5, 6 | Yes | 4.37 | 8.18 | 8.93 |
| 0625 | + | 7.92 | 0, 2, 6 | Yes | 2.60 | 5.51 | 7.90 |
| 1550 | + | 8.04 | 0, 1, 6 | No | 1.58 | NA | NA |
| 0022 | + | 7.83 | 2, 4 | No | 2.48 | NA | NA |
| 0657 | + | 7.85 | 0, 2, 6 | No | Und | 7.61 | 8.76 |
| 1395 | + | 8.24 | 0, 1, 6, 12 | No | Und | NA | NA |
| 9149 | + | 3.61 | 0, 1, 6, 8 | No | Und | 2.91 | Und |
| 0394 | − | 6.51 | 0, 1, 6 | No | Und | 3.08 | 1.48 |
| 0135 | − | 2.28 | Unknown* | Unknown | Und | 5.63 | NA |
| 0349 | + | 6.18 | 0, 1, 6 | No | 2.52 (at 6 wk) | NA | NA |
| 0175 | − | <1.58 | Unknown | Unknown | 2.95 (at 6 wk) | NA | NA |
Und: below detectable level; NA: not available due to insufficiency of plasma samples
*
No record of vaccination, however this child was born in a provincial hospital of the northeastern region of Thailand where the standard of care was to provide at least HB vaccine to all infants born to positive HBsAg mothers.