Figure 6. Whole blood cytokine responses to NOD2 agonists by rs7194886 genotype.
Monocyte-normalized plasma IL-6, TNF-α, IL-1β, and IL-10 levels induced by stimulation of whole blood from 127 healthy female subjects at 37°C for six hours with medium alone, MDP 10 µg/ml (Invivogen) and heat-killed B. pseudomallei 1026b 2.5 × 106 CFU/ml. Boxes show the median and interquartile range; whiskers show upper and lower adjacent values. N= 111 (CC), 15 (CT), 1(TT). p>0.05 for all comparisons between genotypes.