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. Author manuscript; available in PMC: 2013 Dec 24.
Published in final edited form as: N Am J Med Sci (Boston). 2012 Jul 25;5(3):135–140. doi: 10.7156/najms.2012.053135

Figure 1. The TS2-NEO mouse.

Figure 1

A: The TS2-NEO mouse is outwardly normal in appearance, compared to B: negative control littermates. C: TS2-NEO mice were extremely susceptible to dermatitis, with a tendency to scratch on one side. D: Littermates suffered dermatitis less frequently and had smaller more symmetrical lesions. E: Representative quantitative real-time PCR data showing there is no change in relative expression of exon 8 and 8a in TS2-NEO mice compared to littermates in both heart and brain. F: Topology of the Cav1.2 channel showing the location of the G to R mutation in exon 8 at the intracellular side of S6 in domain I.