Table 2.
Steady state plasma levels of unconjugated bilirubin in HbSS individuals before and 12 months after addition of omega-3 fatty acids and potassium thiocyanate to standard management with folic acid and paludrine.
| Study identity number |
Plasma unconjugated bilirubin level (umol/L) |
|
|---|---|---|
| Pretreatment | Posttreatment | |
| 1 | 4.3 | 4.1 |
| 2 | 7 | 4.4 |
| 3 | 25.6 | 11 |
| 4 | 4.2 | 4.5 |
| 7 | 4 | 7.7 |
| 8 | 23 | 9.8 |
| 9 | 4 | 16.5 |
| 10 | 3 | 22 |
| 11 | 10 | 27 |
| 12 | 14 | 20 |
| 13 | 1 | 19.3 |
| 14 | 14 | 21 |
|
| ||
| Median (n = 12) | 5.65 | 13.75 |
|
P value (2-tailed, Mann-Whitney U test pre- versus posttreatment data) |
0.11 (no significant difference) |
|