Table 1.
Estimating SNP-heritability with GCTA v1.11
| Total score | AI | NR | IP | SH | |
|---|---|---|---|---|---|
| NTR/NESDA N=3951 | |||||
| V(G)/Vp | 0.231 | 0.427 | 0.115 | 0.083 | 0.0599 |
| SE | 0.088 | 0.087 | 0.088 | 0.087 | 0.0868 |
| LRT | 7.437 | 26.575 | 1.765 | 0.941 | 0.484 |
| p-value | 0.003 | 1e-07 | 0.09 | 0.2 | 0.2 |
| NTR N=3300 | |||||
| V(G)/Vp | 0.207 | 0.257 | 0.174 | 0.119 | 0.089 |
| SE | 0.106 | 0.105 | 0.106 | 0.105 | 0.104 |
| LRT | 3.773 | 6.349 | 2.738 | 1.291 | 0.757 |
| p-value | 0.03 | 0.006 | 0.05 | 0.1 | 0.2 |
Note: We used a cutoff of 0.025 of genetic resemblance resulting approximately in 1 member per family in all analyses. In the analyses of the combined NTR/NESDA sample an ntr/nesda indicator was used as a covariate. Other covariates were age, gender, their interaction, and a PC controlling for stratification within the Dutch population.