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. 2013 Dec 18;7:23–32. doi: 10.2147/OTT.S54575

Figure 1.

Figure 1

Exposure to T-oligo increased the expression of hnRNP C1/C2. H358, SW1573, MU, and MM-AN cancer cell lines were treated with either diluent, T-oligo, or complementary oligonucleotide for the indicated periods of time and then immunoblotted for hnRNP C1/C2.

Note: (A) T-oligo increased hnRNP C1/C2 expression by 5.2-fold after 6 hours in MU melanoma cells. (B and C) T-oligo upregulated expression by 4.5-fold in MM-AN melanoma cells and by 3.6-fold in H358 cells at 18 hours. (D) T-oligo increased hnRNP C1/C2 by 12.0-fold at 18 hours and 3.0-fold at 24 hours in SW1573 cells. hnRNP C1/C2 proteins are seen as either single or double bands.

Abbreviations: hnRNP C1/C2, heterogeneous nuclear ribonucleoprotein C1 and C2; D, diluent; T, T-oligo; C, complementary oligonucleotide.