Table 2.
Changes in incremental area under the curve (iAUC) for each metabolic parameter after E460F18 loading at 0 and 4 weeks of pitavastatin treatment.
| 0 week | 4 week | P | |
|---|---|---|---|
| Triglycerides (mg/dL) | 3885 (2565–6480) | 2745 (1883–4508) | 0.007 |
| Remnant-like particle cholesterol (mg/dL) | 166 ± 125 | 68 ± 85 | 0.0012 |
| Apolipoprotein E (mg/dL) | 21 ± 29 | 4 ± 13 | 0.1333 |
| Glucose (mg/dL) | 882 ± 2175 | 1491 ± 2216 | 0.2289 |
| Insulin | 2342 (1202–3083) | 2664 (1441–5439) | 0.093 |
| C Cr (mL/minute) | 5048 ± 7975 | 6058 ± 4660 | 0.7752 |
| Albumin creatinine ratio | −68 ± 194 | −194 ± 312 | 0.2424 |
| C UA (mL/minute) | 536 ± 317 | 534 ± 292 | 0.9920 |
| Adjusted urinary excretion of uric acid (mg/kg/hour) | −88 ± 55 | −37 ± 53 | 0.0442 |
Values are shown as mean ± standard deviation. C Cr: creatinine clearance; C UA: uric acid clearance.
iAUC for triglycerides and insulin are shown as median and interquartile range.