Table 5.
Patient | Smoking status |
Percent predicted |
FEV1/FVC ratio |
LLN FEV1/FVC ratio |
Hematology |
Chest radiographs |
Pulmonary function pattern | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
FVC | FEV1 | Total WBC# |
Neut*% | PE | IVM | ATS/ERS Task force£ |
Mannino et al.¥ [16] | Graniteville criteria$ |
||||
1 | Current | 59 | 43 | 0.55 | 0.63 | 9.3 | 73.8 | Yes | Yes | O | Severe O | O |
2 | Current | 40 | 37 | 0.75 | 0.71 | 14.2 | Miss. | Yes | No | U | R | R |
3 | Current | 50 | 58 | 0.79 | 0.67 | 15.2 | Miss. | Yes | No | U | R | R |
4 | Current | 45 | 45 | 0.85 | 0.74 | 19.7 | Miss. | Yes | No | R | R | R |
5 | Nonsmoker | 56 | 46 | 0.73 | 0.76 | 16 | 80 | Yes | No | O | R | M |
6 | Nonsmoker | 68 | 63 | 0.69 | 0.68 | 11 | 75 | No | No | U | Moderate O | O |
7 | Nonsmoker | 71 | 66 | 0.81 | 0.71 | 12.1 | 86 | No | No | U | R | R |
8 | Nonsmoker | 71 | 75 | 0.87 | 0.70 | 14.4 | 79.3 | No | Yes | R | R | R |
9 | Nonsmoker | 66 | 64 | 0.78 | 0.71 | 16.9 | Miss. | Yes | No | U | R | R |
10 | Former | 46 | 37 | 0.81 | 0.71 | 10.3 | 84 | Yes | No | U | R | R |
#×103 cells/μL, *neutrophils.
PE: pulmonary edema; IVM: increased vascular markings; Miss.: missing.
O: obstructive pattern; R: restrictive pattern; M: mixed pattern; U: undetermined pattern.
£Obstructive pattern: FEV1/VC ratio below LLN; Restrictive pattern: TLC below LLN or FEV1/VC ratio ≥ 85% and a reduced VC; mixed: FEV1/VC ratio and TLC below LLN.
¥Obstructive pattern: mild: FEV1/FVC ratio < 70%, FEV1 ≥ 80% of predicted, moderate: FEV1/FVC ratio < 70%, FEV1 ≥ 50%–< 80% of predicted, severe: FEV1/FVC ratio < 70%, FEV1 < 50% of predicted; restrictive pattern: FEV1/FVC ratio ≥ 70% and FVC < 80% of predicted.
$Obstructive pattern: FEV1/FVC ratio ≤ 0.70 and normal, reduced, or increased FEV1 and FVC percent predicted; restrictive pattern FEV1/FVC ratio ≥ 0.75, FEV1 and FVC < 75% of predicted; mixed: FEV1/FVC ratio > 0.70 and < 0.75 FEV1 and FVC < 75% predicted.