Table 2.
Rs# and gene; minor allele and its frequency | Dominant model OR (CI); P value |
Recessive model OR (CI); P value |
Additive model OR (CI); P value |
---|---|---|---|
rs4612601; EPHB2 AA: 0.49 (G) EA: 0.45 (A) |
AAM: 1.09 (0.63–1.9); 0.749 | 0.86 (0.46–1.61); 0.638 | 0.99 (0.69–1.41); 0.951 |
EAM: 1.18 (0.67–2.10); 0.564 | 0.9 (0.52–1.56); 0.709 | 1.02 (0.73–1.43); 0.912 | |
All: 1.13 (0.76–1.69); 0.537 | 0.89 (0.59–1.34); 0.565 | 1.00 (0.79–1.28); 0.969 | |
| |||
rs4263970; EPHB2 AA: 0.47 (T) EA: 0.45 (C) |
AAM: 0.98 (0.57–1.68); 0.932 | 0.88 (0.44–1.75); 0.711 | 0.95 (0.66–1.38); 0.797 |
EAM: 1.08 (0.61–1.9); 0.795 | 0.76 (0.44–1.33); 0.334 | 0.93 (0.66–1.30); 0.665 | |
All: 1.02 (0.69–1.5); 0.918 | 0.81 (0.53–1.25); 0.343 | 0.94 (0.73–1.21); 0.630 | |
| |||
rs822396; ADIPOQ AA: 0.2 (G) EA: 0.15 (G) |
AAM: 0.89 (0.52–1.52); 0.671 | 1.64 (0.37–7.21); 0.511 | 0.96 (0.6–1.54); 0.878 |
EAM: 0.75 (0.44–1.27); 0.288 | 1.1 (0.29–4.09); 0.094 | 0.82 (0.53–1.29); 0.392 | |
All: 0.82 (0.56–1.19); 0.285 | 1.29 (0.49–3.48); 0.601 | 0.88 (0.64–1.22); 0.456 | |
| |||
rs10993994; MSMB AA: 0.2 (C) EA: 0.34 (T) |
AAM: 0.82 (0.48–1.4); 0.472 | 1.04 (0.51–2.10); 0.919 | 0.92 (0.63–1.33); 0.657 |
EAM: 1.04 (0.54–2.00); 0.899 | 0.61 (0.36–1.05); 0.077 | 0.81 (0.56–1.17); 0.258 | |
All: 0.9 (0.6–1.35); 0.611 | 0.75 (0.49–1.14); 0.177 | 0.87 (0.67–1.11); 0.261 | |
| |||
rs1859962; HNF1B AA: 0.49 (G) EA: 0.2 (G) |
AAM: 1.03 (0.61–1.74); 0.905 | 1.23 (0.54–2.81); 0.626 | 1.06 (0.72–1.56); 0.752 |
EAM: 1.38 (0.77–2.45); 0.278 | 1.00 (0.57–1.76); 0.997 | 1.13 (0.79–1.6); 0.508 | |
All: 1.16 (0.8–1.69); 0.431 | 1.06 (0.67–1.69); 0.790 | 1.09 (0.85–1.4); 0.503 | |
| |||
rs7501939; HNF1B AA: 0.48 (C) EA: 0.49 (T) |
AAM: 1.34 (0.73–2.47); 0.343 | 2.42 (1.31–4.47); 0.0046 | 1.56 (1.08–2.27); 0.0193 |
EAM: 0.82 (0.5–1.35); 0.439 | 1.13 (0.54–2.38); 0.742 | 0.93 (0.65–1.33); 0.692 | |
All: 0.99 (0.68–1.45); 0.981 | 1.76 (1.11–2.79); 0.0167 | 1.18 (0.92–1.52); 0.187 | |
| |||
rs4430796; HNF1B AA: 0.34 (A) EA: 0.47 (A) |
AAM: 0.57 (0.34–0.97); 0.0383 | 0.64 (0.29–1.42); 0.272 | 0.67 (0.46–0.99); 0.0431 |
EAM: 1.27 (0.7–2.3); 0.439 | 0.98 (0.57–1.68); 0.946 | 1.07 (0.76–1.51); 0.689 | |
All: 0.81 (0.55–1.18); 0.273 | 0.86 (0.59–1.33); 0.500 | 0.87 (0.69–1.12); 0.279 | |
| |||
rs2070874; IL4 AA: 0.45 (T) EA: 0.2 (T) |
AAM: 0.94 (0.54–1.64); 0.824 | 1.45 (0.7–3.0); 0.314 | 1.08 (0.73–1.59); 0.700 |
EAM: 0.65 (0.38–1.11); 0.115 | 0.92 (0.22–3.93); 0.916 | 0.72 (0.45–1.14); 0.161 | |
All: 0.82 (0.57–1.17); 0.275 | 1.32 (0.7–2.49); 0.386 | 0.94 (0.71–1.24); 0.649 | |
| |||
rs627839; RNASEL AA: 0.46 (T) EA: 0.45 (T) |
AAM: 1.2 (0.7–2.06); 0.511 | 1.63 (0.78–3.42); 0.192 | 1.24 (0.85–1.83); 0.252 |
EAM: 0.86 (0.5–1.47); 0.571 | 0.99 (0.55–1.8); 0.986 | 0.94 (0.67–1.32); 0.710 | |
All: 1.01 (0.69–1.48); 0.952 | 1.21 (0.76–1.91); 0.427 | 1.06 (0.83–1.37); 0.632 | |
| |||
rs4962416; CTBP2 AA: 0.23 (C) EA: 0.23 (C) |
AAM: 0.9 (0.5–1.59); 0.709 | 5.65 (0.62–51.7); 0.125 | 1.05 (0.63–1.74); 0.861 |
EAM: 1.69 (1.02–2.8); 0.0415 | 1.72 (0.68–4.31); 0.251 | 1.52 (1.02–2.26); 0.0384 | |
All: 1.28 (0.88–1.85); 0.198 | 2.12 (0.92–4.9); 0.0784 | 1.31 (0.97–1.78); 0.083 |
Bolded values denote statistically significant associations.