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. Author manuscript; available in PMC: 2014 Dec 5.
Published in final edited form as: Eur J Pharmacol. 2013 Oct 5;721(0):10.1016/j.ejphar.2013.09.053. doi: 10.1016/j.ejphar.2013.09.053

Figure 1.

Figure 1

Diuresis measurements over 6 h. (A) Effects of different volumes of saline (n=8); (B) effects of repeated administration of 10 ml/kg saline (n=8); and (C) effects of furosemide or U50,488 (n=8) (C) on urine output; points above V indicate effects of vehicle injection. Abscissae: volume of saline (A); iteration of saline determination since first determination (B); or drug dose (C). Ordinates: urine output over 6 h in ml per kg body weight. Asterisks indicate doses that had effects significantly different from 10 ml•kg−1 vehicle * P<0.05; *** P<0.001