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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Int J Obes (Lond). 2013 Aug 8;39(1):98–104. doi: 10.1038/ijo.2013.146

Figure 4.

Figure 4

Physical activity levels ‘track’ into adulthood and predict adult adiposity in females only. (a) Among a/a offspring, dark-period physical activity in juveniles predicts that in adulthood only in females. Each plot includes 11 LL offspring from 7 litters and 11–12 OL offspring from 8 litters. (b) Adult physical activity predicts adult adiposity, again only in females (same offspring as in panel A). (c) Mediational regression analysis focused on a/a female offspring. Fetal growth restriction predicts adult adiposity (top), but this direct pathway is abrogated when adult physical activity is included in the model (bottom), indicating that induced alterations in physical activity mediate the obesogenic effect of fetal growth restriction. (Analysis includes data on female offspring from panels a & b.)