Table 1. Summary of major changes in RECIST 1.1 compared with RECIST 1.0.

RECIST guideline	RECIST 1.1	RECIST 1.0
No. of target lesions	Up to 2 per organ; up to 5 in total	Up to 5 per organ; up to 10 in total
Assessment of LNs	Short-axis measurements should be used and recorded; ≥15 mm, target lesions; ≥10 mm but <15 mm, non-target lesions; <10 mm,non-pathological	No clear guideline provided
Clarification of disease progression	20% increase in the sum of target lesions and 5-mm absolute increase are required	20% increase in the sum of target lesions (no minimum absolute size increase) is required
FDG-PET scan	Included only in the detection of new lesions	Not included

RECIST 1.0, Response Evaluation Criteria in Solid Tumors guideline version 1.0; RECIST 1.1, Response Evaluation Criteria in Solid Tumors guideline version 1.1; LNs, lymph nodes; FDG, fluorodeoxyglucose; PET, positron emission tomography.