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. 2013 Dec 26;7:120. doi: 10.3389/fnsys.2013.00120

Figure 4.

Figure 4

Recipient rat performance on DNMS trials with unfamiliar superimposed delays facilitated by donor rat mediated SR stimulation. (A) Individual DNMS performance of five different recipient rats subjected to trials with 8, 12, and 16 s delays shown for trials in which no stimulation was delivered (No Stim) or on trials on which a simultaneously paired donor rat delivery of MIMO SR CA1 stimulation pattern was delivered (Stim). The similarity across each graph indicates generality of facilitated performance on imposed delay trials with delivery of donor rat MIMO generated CA1 SR stimulation. Asterisks *p < 0.01, **p < 0.001, Stim donor rat vs. No Stim. (B) Overall performance of recipient rats (n = 5) is shown as mean (±s.e.m.) % correct trials with no delays (green dot−0.0 s values) in comparison to trials with variable delays (8, 12, 16 s) without donor rat stimulation (green triangles-No Stim) delivered during the trial [F(3, 279) = 3.61, p < 0.001]; and performance on trials with the same delays but including donor rat MIMO strong SR code stimulation (Recipient Stim, red squares) which significantly improved performance compared to No Stim trials [F(1, 279) = 9.82, p < 0.001]. For comparison a plot of the average performance level of rats fully trained (n = 20) on the task at the same delays (Trained subjects) is shown (black squares) for comparison to recipient rat performance on stimulated trials [F(1, 1349) = 13.48, p = 0.001, Trained subjects > recipient rats]. Symbols: *p < 0.01, **p < 0.001, p < 0.01, p = 0.001.