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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Bioorg Med Chem. 2013 Aug 20;21(21):10.1016/j.bmc.2013.08.022. doi: 10.1016/j.bmc.2013.08.022

Scheme 1.

Scheme 1

i) K2CO3 (9 eq), CH3CN, RT, 48 h; ii) 1-Propanol, reflux 16-24 h. R: varies (see Table 1); R1: H or 6-Cl; n: 1 or 2; X=C, 2-NO2; X=N, 3-NO2