Table 1.
Antibacterial spectrum of 11
| Test Strain | Minimum inhibitory concentration (μg/ml) | ||
|---|---|---|---|
| Sphaerimicin A | Chloramphenicol* | Linezolid* | |
| Streptococcus pneumoniae ATCC 496193THB3 | 1 | 2 | 1 |
| Streptococcus pneumoniae ATCC 49619 | 16 | 2 | 1 |
| Streptococcus pyogenes ATCC 12344 | 16 | 2 | 1 |
| Staphylococcus aureus ATCC 6538P | 4 | 8 | 2 |
| Staphylococcus aureus 10925 | 8 | 16 | 2 |
| Staphylococcus epidermidis ATCC 14990 | 8 | 4 | 1 |
| Enterococcus faecalis ATCC 29212 | 2 | 8 | 2 |
| Enterococcus faecium ATCC 19434 | 2 | 8 | 4 |
| Moraxella catarrhalis ATCC 25238 | 4 | 1 | 4 |
| Haemophilus influenzae ATCC 49247 | 8 | 1 | 8 |
| Haemophilus influenzae Rd | 32 | 1 | 8 |
| Escherichia coli ATCC 47076 | >128 | 8 | >128 |
| Escherichia coli ATCC 25922 | >128 | 4 | >128 |
| Klebsiella pneumoniae ATCC 13883 | >128 | 4 | >128 |
| Enterobacter cloacae ATCC 13047 | >128 | 8 | >128 |
| Serratia marcescens ATCC 13880 | >128 | 8 | 128 |
| Proteus vulgaris ATCC 13315 | >128 | 4 | 8 |
| Pseudomonas aeruginosa ATCC 15692 | >128 | 64 | >128 |
| Stenotrophomonas maltophilia ATCC 13637 | >128 | 4 | >128 |
| Acinetobacter baumannii ATCC 19606 | >128 | 128 | 128 |
*
Chloramphenicol and linezolid were used as a standard in this assay.