Fig. 2.

(A) Aβ aggregation at several concentrations of 1 was monitored for 48 h, as described in Fig. 1A. After 48 h, 1% wt/wt of Aβ seeds was added, and aggregation was monitored for another week. (B and C) AFM images obtained just before (B) and 1 h after (C) seed addition. The images shown here are representative of two experiments. (D) Aggregation of Aβ1–40 (50 μM, black lines), 1–42 (50 μM, red lines), Aβ1–40:1–42 in a 3:1 ratio (50 μM, green lines) were monitored as described in Fig. 1A (but note the lower Aβ concentrations).