. Author manuscript; available in PMC: 2013 Dec 26.

Published in final edited form as: Radiat Res. 2010 Jun;173(6):10.1667/RR1661.1. doi: 10.1667/RR1661.1

TABLE 1.

Comparison of Yeast and Mammalian Cells for Cell Cycle Dependence of Sensitivity to Ionizing Radiation for Cell Killing and Genotoxicity

	Yeast	Mammalian cells
Cell killing	G₁ > S and G₂ (23, 24)	M > S > G₁ and G₂ (7, 8)
Chromosomal aberrations	No experimental data	G₂ > S > G₁ (9-14)
Mutation induction	G₁ > early S > late S and G₂ (26)	G₁ > early S > late S (18-22)
Homologous DNA deletions	S and G₂ > G₁ and G₀ (this study)	No experimental data

Notes. Cell cycle phase sensitivity to ionizing radiation was tabulated for measurements performed in yeast and mammalian cell systems. The cell cycle phases are listed in order of most sensitive to least sensitive to radiation exposure.