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. 2013 Dec 26;8(12):e83238. doi: 10.1371/journal.pone.0083238

Table 1. Comparison of clinical and pathologic characteristics by tumor SHBG intensity.

SHBG IHC score
1 (weak) 2 (moderate) 3 (strong) p value
N Total N 65 93 90
Age (years old): 0.200
≤49 57 19 19 19
(33.3%) (33.3%) (33.3%)
≥50 175 41 66 68
(23.4%) (37.7%) (38.9%)
Missing 16
Histological subtype: 0.022
Serous 163 41 55 67
(25.2%) (33.7%) (41.1%)
Muci+Endo 37 17 13 7
(45.0%) (35.1%) (18.9%)
Clea+Mixe+Undi 27 4 12 11
(14.8%) (44.4%) (40.7%)
Others or unclassified 21
FIGO Stage: 0.018
I+II 46 16 19 11
(34.8%) (41.3%) (23.9%)
III 117 32 42 43
(27.4%) (35.9%) (36.8%)
IV 79 17 26 36
(21.5%) (32.9%) (45.6%)
Not staged or missing 6
Histological Grade: 0.020
Well 19 6 10 3
(31.6%) (52.6%) (15.8%)
Moderate 62 18 26 18
(29.0%) (41.9%) (29.0%)
Poor 133 31 43 59
(23.3%) (32.3%) (44.4%)
Not graded or missing 34

Muci, Mucinous tumor; Endo, Endometrioid; Clea, Clear cell; Mixe, Mixed epithelial tumor; Undi, Undifferenciated tumor.