Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Dec 26;8(12):e83458. doi: 10.1371/journal.pone.0083458

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2013 Tarrade et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A-B) Light microscopy morphological analysis of placentas on D28 from C and HH fetuses. Numerous light vesicles (LV) are located in the trophoblastic layer (TL) of HH (B) compared to C placenta (A). A’ and B’ represent the high magnification of the zone indicated by a star. Scale bar: 100 µm. (C-D) Transmission electron microscopy of placentas on D28 of gestation from C and HH fetuses. Light vesicles were identified as lipid droplets (LD) in the trophoblastic layer (TL) of HH (right panel) compared to C placenta (left panel). EC: Endothelial cell; FV: Fetal Vessel; MC: Maternal Compartment. Scale bar: 5 µm. (E-F) Distribution of lipid droplets on D6 in C and HH blastocysts Fluorescent immunodetection of adipophilin (green), Nile red (red), and DNA (blue) from C (E) and HH (F) blastocysts. In HH blastocysts, abnormal accumulation of lipid droplets is observed around the nuclei (F’), colocalized with adipophilin staining (F’’), in contrast to C blastocysts (E-E”). Scale bar: 20 µm.