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. 2013 Dec 26;8(12):e83673. doi: 10.1371/journal.pone.0083673

Table 2. Resume of the significant two-tailed bivariate correlation results between ERBB2 RNA, erbB-2 protein expression levels, and clinicopathological features of mammary lesions.

Protein RNA Sequence Variants
CB11/Int CBE356/Ext Conc ratio X 100 Lesion/normal ratio g.271 T>G g.280 G>A g.311 G>A g.327 T>G g.335 C>T g.1754 A>C g.1914 G>C g.1994 del A
Clinicopathological Features
Histological Class n#* n*
Age (Years) p*
Lesion size p* p*
Pleomorphism n*
Lesions number n*
Lymphatic invasion p** p** p**
Vascular infiltration p*
Clinical Outcome n* n*
Protein Ni
CB11/int p* p* p*
CBE356/ext
RNA Ni
Conc_ratio_X_100 p*

The significant values of the Pearson's correlation analysis were confirmed by the Spearman's test.

(#) Significant correlation only by Spearman's test.

(*) Correlation is significant at the 0.05 level.

(**) Correlation is significant at the 0.01 level.

(p: positive; n: negative) Indication of the direction of the relationship between variables.

(Ni) Sequence variants were not included in correlation test with RNA RT-qPCR and protein IHC.