Figure 1. Locomotor activity of Cry1^-/- and Cry2^-/- mice.

Five days average of daily distribution of locomotor activity of Cry1^-/-, Cry2^-/- and wild type littermate mice, as recorded in a running wheel set up (A) or by motion detectors (B). Upper and lower panels show activity distributions for Cry1^-/- mice and their littermates and Cry2^-/- mice and their littermates, respectively. (C) Average position of the onset of activity relative to the offset of light during exposure to LD 12:12 in Cry1^-/-, Cry2^-/- and their littermate mice recorded by running wheels (open symbols) and motion detectors (closed symbols). White and grey background indicates day and night, respectively. Error bars indicate standard error of the mean (s.e.m.).