Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Dec 26;8(12):e83602. doi: 10.1371/journal.pone.0083602

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2013 Destici et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

Relative mRNA expression profiles of core clock genes Bmal1 (A) and Per2 (B) and the clock-controlled genes Dbp (C) and Pk2 (D) in the SCN of light entrained (LD) wild type (black), Cry1^-/- (green) and Cry2^-/- (red) mice, as measured by RT-qPCR. For each genotype, mRNA levels (mean ± s.e.m) are expressed relative to the peak of expression (set at 100%) and fitted with a wave curve. The two-way ANOVA test revealed a significant effect of genotype and time interaction (*p<0.05). Data at ZT0 and ZT24 are double-plotted for easier visualization of daily expression. The bar above panels indicates time of light on and off.