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. 2013 Dec 26;8(12):e83602. doi: 10.1371/journal.pone.0083602

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© 2013 Destici et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Urine was collected at 4(black), Cry1^-/- (green), and Cry2^-/- (red) mice (± s.e.m; n = 8 per genotype). Data were fitted with a wave curve and analysis of variance revealed significant difference among genotypes (p<0.001). Data at ZT0 and ZT24 are double-plotted for easier visualization of daily expression. The bar below panel indicates lights on and off.