Table 2. Summary statistics for optic nerve DTI (mean* with 95% CI).
Axial Diffusivity |
Radial diffusivity |
|||||
---|---|---|---|---|---|---|
Unaffected eye** | Affected eyeΨ | Inter-ocular difference | Unaffected eye** | Affected eyeΨ | Inter-ocular difference | |
1.80 | 1.54 | -0.27 | 0.93 | 0.88 | -0.05 | |
Baseline | (1.72 to 1.85) | (1.44 to 1.61) | (-0.35 to -0.19) | (-.84 to 0.97) | (0.82 to 0.93) | (0.09 to 0.02) |
p = 0.90 | p < 0.001 | p = 0.73 | p = 0.10 | |||
1.81 | 1.61 | -0.20 | 0.93 | 0.91 | -0.02 | |
1 month | (1.75 to 1.86) | (1.54 to 1.67) | (-0.27 to -0.13) | (0.87 to 0.97) | (0.84 to 0.96) | (-0.07 to 0.02) |
p = 0.91 | p < 0.001 | p = 0.82 | p = 0.25 | |||
1.84 | 1.74 | -0.10 | 0.94 | 0.99 | 0.05 | |
3 months | (1.75 to 1.88) | (1.63 to 1.80) | (-0.16 to – 0.04) | (0.86 to 0.97) | (0.92 to 1.05) | (0.03 to 0.11) |
p = 0.59 | p = 0.003 | p = 0.96 | p = 0.023 | |||
1.79 | 1.77 | -0.02 | 0.92 | 1.0 | 0.08 | |
6 months | (1.71 to 1.82) | (1.71 to 1.81) | (-0.06 to 0.05) | (0.85 to 0.96) | (0.94 to 1.05) | (0.04 to 0.14) |
p = 0.61 | p = 0.74 | p = 0.62 | p = 0.003 | |||
1.76 | 1.82 | 0.06 | 0.93 | 1.07 | 0.16 | |
12 months | (1.68 to 1.80) | (1.75 to 1.86) | (0.02 to 0.12) | (0.84 to 0.95) | (1.01 to 1.11) | (0.11 to 0.22) |
p = 0.26 | p = 0.013 | p = 0.44 | p < 0.001 |
* Measurement units are x10- 3 mm2s-1.
** Significance values from unpaired Student’s t-tests between unaffected nerve and control nerves
Ψ Significance values paired Student’s t-tests between affected and unaffected nerves.