Table 3. Associations of SNPs with EBVs of five milk production traits (LSM±SE).
SNP ID | Genotype | MY | FY | PY | FP | PP |
SNP1 | TT | 538.94±151.12A | 2.21±4.78 | 14.65±4.33Aa | −17.91±4.99B | −2.53±2.27 |
TG | 397.51±150.05B | 5.06±4.75 | 10.79±4.29b | −9.39±4.95A | −1.88±2.25 | |
GG | 284.31±157.94B | 4.02±5.02 | 6.48±4.52Bb | −6.36±5.26A | −2.54±2.37 | |
P-value | 0.0002* | 0.1849 | <.0001* | <.0001* | 0.6132 | |
σ2 a/σ2 P | 1.28E-02 | 1.46E-04 | 1.76E-02 | 1.75E-02 | 9.36E-05 | |
SNP2 | TT | 434.81±148.54 | 3.87±4.69 | 11.62±4.26 | −12.14±4.89 | −2.24±2.23 |
CT | 508.20±200.83 | 4.61±6.52 | 16.86±5.73 | −14.24±6.90 | 0.69±3.05 | |
P-value | 0.5916 | 0.8706 | 0.1769 | 0.6700 | 0.1644 | |
σ2 a/σ2 P | 1.14E-02 | 8.57E-04 | 1.54E-02 | 7.16E-03 | 8.01E-05 | |
SNP3 | GG | 459.49±152.55 | 0.45±4.83 | 11.40±4.37 | −16.83±5.05B | −3.25±2.29 |
GA | 453.63±149.91 | 5.43±4.74 | 12.37±4.29 | −11.12±4.95A | −2.08±2.25 | |
AA | 354.44±154.36 | 4.51±4.89 | 10.24±4.42 | −8.42±5.12A | −1.07±2.32 | |
P-value | 0.1532 | 0.0121 | 0.3828 | 0.0003* | 0.0691 | |
σ2 a/σ2 P | 2.70E-03 | 2.75E-03 | 4.97E-04 | 1.19E-02 | 4.43E-03 | |
SNP4 | CC | 431.17±156.89 | −1.32±4.99 | 9.82±4.49 | −17.71±5.22 | −3.91±2.36 |
CT | 424.36±149.83 | 4.81±4.74 | 11.68±4.29 | −10.76±4.94 | −1.84±2.25 | |
TT | 457.63±151.76 | 4.69±4.81 | 12.55±4.35 | −12.00±5.02 | −2.04±2.28 | |
P-value | 0.7771 | 0.0089 | 0.3382 | 0.0079 | 0.0890 | |
σ2 a/σ2 P | 2.46E-04 | 4.56E-03 | 1.70E-03 | 2.97E-03 | 1.89E-03 | |
SNP5 | GG | 344.41±150.02C | 2.66±4.74 | 8.82±4.29C | −10.05±4.95A | −2.12±2.25 |
GA | 495.03±150.64B | 5.12±4.77 | 13.62±4.32B | −13.12±4.97A | −2.19±2.26 | |
AA | 823.33±170.87A | 5.55±5.48 | 23.26±4.88A | −24.40±5.76B | −3.06±2.58 | |
P-value | <.0001* | 0.2244 | <.0001* | <.0001* | 0.8023 | |
σ2 a/σ2 P | 5.49E-02 | 6.19E-04 | 5.99E-02 | 4.59E-02 | 1.27E-03 | |
SNP6 | TT | 462.08±148.76A | 3.79±4.70 | 12.14±4.26 | −13.26±4.90B | −2.61±2.23B |
TC | 243.24±159.42B | 3.91±5.08 | 8.36±4.56 | −4.82±5.32A | 0.77±2.39A | |
CC | 692.83±560.50AB | 42.14±18.70 | 13.94±15.92 | 20.02±20.08AB | −7.34±8.62AB | |
P-value | 0.0036* | 0.1070 | 0.1282 | 0.0005* | 0.0032* | |
σ2 a/σ2 P | 3.38E-02 | 2.39E-01 | 6.27E-03 | 9.24E-02 | 4.75E-02 | |
SNP7 | AA | 339.04±150.02C | 2.53±4.74 | 8.68±4.29C | −9.97±4.95A | −2.08±2.25 |
AG | 501.70±150.64B | 5.22±4.77 | 13.82±4.31B | −13.28±4.97A | −2.21±2.26 | |
GG | 834.06±171.36A | 6.04±5.49 | 23.36±4.89A | −24.24±5.78B | −3.30±2.59 | |
P-value | <.0001* | 0.1558 | <.0001* | <.0001* | 0.6942 | |
σ2 a/σ2 P | 5.73E-02 | 1.13E-03 | 6.01E-02 | 4.43E-02 | 2.05E-03 | |
SNP8 | TT | 344.62±150.02Ba | 2.66±4.74 | 8.82±4.29C | −10.05±4.95A | −2.12±2.25 |
TC | 494.59±150.61Bb | 5.12±4.77 | 13.71±4.31B | −13.11±4.97A | −2.09±2.26 | |
CC | 843.98±171.90A | 5.54±5.51 | 23.05±4.91A | −25.15±5.79B | −3.92±2.59 | |
P-value | <.0001* | 0.2246 | <.0001* | <.0001* | 0.4362 | |
σ2 a/σ2 P | 1.58E-02 | 3.13E-05 | 1.41E-02 | 1.49E-02 | 1.79E-03 | |
SNP9 | AA | 63.93±148.71 | 3.85±4.69 | 12.23±4.26 | −13.26±4.90a | −2.58±2.23a |
AG | 158.72±164.82 | 4.10±5.27 | 6.31±4.71 | −1.44±5.53b | 1.52±2.48b | |
P-value | 0.0001* | 0.9233 | 0.0081 | <.0001* | 0.0007* | |
σ2 a/σ2 P | 5.66E-03 | 5.46E-03 | 3.32E-02 | 1.01E-02 | 2.72E-08 | |
SNP10 | CC | 501.00±150.82Aa | 1.85±4.77 | 13.29±4.32Aa | −16.89±4.98B | −2.70±2.26 |
CT | 422.36±150.25a | 5.99±4.75 | 11.57±4.30a | −9.31±4.96A | −1.89±2.25 | |
TT | 259.26±157.97Bb | 2.35±5.02 | 6.45±4.52Bb | −7.21±5.26A | −1.72±2.38 | |
P-value | 0.0012* | 0.0201 | 0.0013* | <.0001* | 0.4489 | |
σ2 a/σ2 P | 1.43E-02 | 4.55E-03 | 1.50E-02 | 1.18E-02 | 6.12E-04 | |
SNP11 | CC | 598.73±151.49A | 5.93±4.79 | 15.94±4.34A | −16.12±5.01B | −3.16±2.27 |
CA | 383.22±150.00B | 3.06±4.74 | 10.37±4.29B | −11.07±4.95A | −1.88±2.25 | |
AA | 255.05±157.43B | 2.09±5.01 | 6.77±4.51B | −7.19±5.24A | −1.21±2.37 | |
P-value | <.0001* | 0.1087 | <.0001* | 0.0003* | 0.0926 | |
σ2 a/σ2 P | 2.20E-02 | 6.18E-04 | 1.97E-02 | 1.26E-02 | 2.95E-03 | |
SNP12 | AA | 808.89±168.51A | 8.45±5.39 | 22.09±4.82A | −20.81±5.67B | −3.73±2.54 |
AC | 583.80±154.65A | 7.42±4.91 | 17.17±4.43A | −13.98±5.13AB | −1.49±2.32 | |
CC | 367.38±149.03B | 2.59±4.71 | 9.43±4.27B | −10.99±4.91A | −2.26±2.23 | |
P-value | <.0001* | 0.0069 | <.0001* | 0.0035* | 0.2912 | |
σ2 a/σ2 P | 2.39E-02 | 8.04E-03 | 3.27E-02 | 5.38E-03 | 1.37E-04 | |
SNP13 | TT | 521.16±150.22A | 4.11±4.75 | 13.67±4.30Aa | −15.15±4.96Bc | −2.95±2.25 |
TG | 384.39±150.51Ba | 3.61±4.76 | 10.59±4.31a | −10.49±4.97b | −1.66±2.26 | |
GG | 157.36±167.47Bb | 3.95±5.36 | 4.48±4.79Bb | −1.64±5.63Aa | −0.40±2.52 | |
P-value | <.0001* | 0.9473 | 0.0002* | <.0001* | 0.0521 | |
σ2 a/σ2 P | 2.89E-02 | 7.47E-06 | 2.43E-02 | 3.36E-02 | 4.86E-03 |
Within the same column with different superscripts means P<0.01; a,b within the same column with different superscripts means P<0.05.
P indicates the significant association after Bonferroni correction for multiple testing at the significance level α = 0.05; σ2 a/σ2 P represents the proportion of variance explained by a SNP.