Table 1. Status of EGFR mutation and Met amplification and HGF expression in the culture medium of each cell line.
| Cell line | EGFR mutation status | Met amplification | HGF production (ng/105cells/24hr) |
|---|---|---|---|
| HCC827 | E746_A750del | - | <0.03 |
| HCC827ER | E746_A750del | + | <0.03 |
| HCC827/Vec | E746_A750del | - | <0.03 |
| HCC827/HGF#24 | E746_A750del | - | 284±29 |
| HCC827/HGF#28 | E746_A750del | - | 121±21 |
| PC-9 | E746_A750del | - | <0.03 |
| PC-9 KGR1 | E746_A750del/T790M | - | <0.03 |
| H1975 | L858R/T790M | - | <0.03 |
| H1975/Vec | L858R/T790M | - | <0.03 |
| H1975/HGF | L858R/T790M | - | 370±24 |
| MRC-5 | wild | - | 88±9.0 |