Fig. 2.

Amino acid alignment of the hypervariable region with a variable number of (N)_1–4/Y repeats that were excluded in the evolutionary sequence analysis. Several gaps must be introduced to maximize homology. Flanking amino acids shown in bold are conserved. Amino acid sequence among replicate variants (as shown in Fig. 1) is the same, except for an amino acid difference for replicate D2-38 (position 390, Y → H). The numbers above the alignment represent the position in the overall sequence alignment, including gaps.