TABLE 2.
Differentially expressed (>2-fold) miRNA in THC-induced MDSC relative to control BM precursors
| miRNA | Fold change | Chromosome location | Seed sequencea | miRBase accession number |
|---|---|---|---|---|
| Overexpressed | ||||
| mmu-miR-690 | 6.8 | Chr16 | AAGGCUA | MIMAT0003469 |
| mmu-miR-22 | 2.5 | Chr11 | AGCUGCC | MIMAT0000531 |
| mmu-miR-361 | 2.4 | ChrX | UAUCAGA | MIMAT0000704 |
| mmu-miR-1195 | 2.3 | Chr17 | GAGUUCG | MIMAT0005856 |
| mmu-miR-20a | 2.2 | Chr14 | AAAGUGC | MIMAT0000529 |
| mmu-miR-875-3p | 2.1 | Chr15 | CUGAAAA | MIMAT0004938 |
| mmu-miR-15b | 2.1 | Chr3 | AGCAGCA | MIMAT0000124 |
| mmu-miR-27a | 2.0 | Chr8 | UCACAGU | MIMAT0000537 |
| mmu-miR-139-5p | 2.0 | Chr7 | CUACAGU | MIMAT0000656 |
| mmu-miR-202-5p | 2.0 | Chr7 | UCCUAUG | MIMAT0004546 |
| Underexpressed | ||||
| mmu-miR-324-5p | −2.0 | Chr11 | GCAUCCC | MIMAT0000555 |
| mmu-miR-335-5p | −3.3 | Chr6 | CAAGAGC | MIMAT0000766 |
| mmu-miR-762 | −3.7 | Chr7 | GGGCUGG | MIMAT0003892 |
a 7-mer seed sequence (bases 2–8).