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. 2013 Nov 19;288(52):37319–37331. doi: 10.1074/jbc.M113.492793

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© 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 4. — Fibrosis markers in UUO-induced kidney injury. A, immunoblotting for E-cadherin expression and Smad2 phosphorylation in the wild-type and PAR2^−/− kidneys at day 7 post-UUO. B, histogram showing the relative expression of E-cadherin in the UUO-induced kidney injury in each group (mean ± S.E.; *, p < 0.05, n = 8). C, mRNA expression assessed by quantitative real-time PCR for Ctgf and D, Tgfb1 in the UUO-induced kidney injury at day 7 in the wild-type and PAR2^−/− mice (fold-change over contralateral kidney, mean ± S.E.; *, p < 0.05; **, p < 0.01, n = 8).