Table 1.
Molecular evolution analyses of Trittame loki major ICK toxin clades.
| SLAC a | FEL b | REL c | MEME d | FUBAR e | Integrative f | BSR g | PAML h | |||
|---|---|---|---|---|---|---|---|---|---|---|
| SLAC + FEL + REL + MEME | M8 | M2a | ||||||||
| Clade I | ω > 1 i | 0 | 2 | 22 | 2 sites | 13 | 22 | 3 | 17 | 12 |
| ω < 1 j | 0 | 4 | 0 | 0 | 4 | (9 + 8) | (6 + 6) | |||
| ω = | 1.41 | - | 1.62 | - | - | 1.81 | 1.81 | |||
| Clade II | ω > 1 i | 0 | 0 | 0 | 0 sites | 0 | 0 | 4 | 5 | 3 |
| ω < 1 j | 3 | 11 | 0 | 14 | 15 | (1 + 4) | (1 + 2) | |||
| ω = | 0.42 | - | 0.47 | - | - | 0.67 | 0.67 | |||
Legend: a: Single Likelihood Ancestor Counting; b: Fixed-effects likelihood; c: Random-effects likelihood; d: Sites detected as experiencing episodic diversifying selection (0.05 significance) by the Mixed Effects Model Evolution (MEME); e: Fast Unconstrained Bayesian AppRoximation; f: Sites detected in common by SLAC, FEL, REL, MEME and FUBAR (the integrative approach); g: Number of branches detected by the branch-site REL (Random effects likelihood) test as episodically diversifying; h: Positively selected sites detected by the Bayes Empirical Bayes approach implemented in M8 and M2a. Sites detected at 0.99 and 0.95 significance are indicated in the parenthesis; i: Number of positively selected sites at 0.05 significance (for SLAC, FEL) or 50 Bayes factor (for REL); or number of sites under pervasive diversifying selection at 0.9 posterior probability (FUBAR); j: Number of negatively selected sites at 0.05 significance (for SLAC, FEL) or 50 Bayes factor (for REL); or number of sites under pervasive purifying selection at 0.9 posterior probability (FUBAR); ω: mean dN/dS.