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. Author manuscript; available in PMC: 2014 Nov 1.

Published in final edited form as: Stroke. 2013 Sep 5;44(11):10.1161/STROKEAHA.113.001304. doi: 10.1161/STROKEAHA.113.001304

Table 3.

Risk of Lobar ICH by Apo E carrier status and Hypercholesterolemia vs. No Hypercholesterolemia

	Discovery Sample				Replication Sample
ApoE2 carriers vs. E3/E3	Case	Control	OR (CI)	p	Case	Control	OR (CI)	p
-Normocholesterolemia	33 (39%)	53 (24%)	2.06 (1.21, 3.51)	0.01	86 (36%)	20 (17%)	2.87 (1.65, 4.97)	0.0002
-Hypercholesterolemia	28 (46%)	27 (18%)	3.93 (2.04, 7.55)	<0.0001	24 (22%)	28 (16%)	1.69 (0.91, 3.32)	0.09
ApoE4 carriers vs. E3/E3
-Normocholesterolemia	42 (45%)	73 (30%)	1.90 (1.17, 3.11)	0.01	112 (42%)	40 (29%)	1.82 (1.17, 2.83)	0.008
-Hypercholesterolemia	33 (50%)	73 (37%)	1.71 (0.98, 3.00)	0.08	54 (39%)	49 (25%)	2.00 (1.25, 3.21)	0.004