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. Author manuscript; available in PMC: 2013 Dec 27.
Published in final edited form as: JAMA. 2012 Oct 17;308(15):10.1001/jama.2012.13088. doi: 10.1001/jama.2012.13088

Figure 1.

Figure 1

Flowchart of the Study for the Overall Series

A patient is assumed to not have Lynch syndrome if the tumor is mismatch repair (MMR) proficient; germline MMR gene analysis was not performed for most of these individuals. CRC indicates colorectal cancer.