Table 1.

True parameter values under the Cox proportional hazards model with the marker main effects (Main) of markers 1 to 15 (M1–M15), the marker and treatment 1 interaction (MT1), and the marker and treatment 2 interaction (MT2).

	Ml	M2	M3	M4	M5	M6	M7	M8	M9	MIO	M11	M12	M13	M14	M15
	Null Model
Main	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
MTl	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
MT2	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
	Alternative Model 1
Main	−0.50	−0.50	0.50	0.50	−0.30	−0.30	0.30	0.30	−0.30	−0.30	0.30	0.30	0.00	0.00	0.00
MTl	0.00	0.00	0.00	0.00	−0.70	−0.70	0.70	0.70	0.00	0.00	0.00	0.00	0.00	0.00	0.00
MT2	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	−0.70	−0.70	0.70	0.70	0.00	0.00	0.00
	Alternative Model 2
Main	−1.00	0.00	0.00	−0.25	−0.25	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
MTl	0.00	−1.00	0.00	−1.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
MT2	0.00	0.00	−1.00	0.00	−1.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00