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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Contemp Clin Trials. 2013 Sep 25;36(2):10.1016/j.cct.2013.09.009. doi: 10.1016/j.cct.2013.09.009

Table 1.

True parameter values under the Cox proportional hazards model with the marker main effects (Main) of markers 1 to 15 (M1–M15), the marker and treatment 1 interaction (MT1), and the marker and treatment 2 interaction (MT2).

Ml M2 M3 M4 M5 M6 M7 M8 M9 MIO M11 M12 M13 M14 M15
Null Model
Main 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
MTl 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
MT2 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00

Alternative Model 1
Main −0.50 −0.50 0.50 0.50 −0.30 −0.30 0.30 0.30 −0.30 −0.30 0.30 0.30 0.00 0.00 0.00
MTl 0.00 0.00 0.00 0.00 −0.70 −0.70 0.70 0.70 0.00 0.00 0.00 0.00 0.00 0.00 0.00
MT2 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 −0.70 −0.70 0.70 0.70 0.00 0.00 0.00

Alternative Model 2
Main −1.00 0.00 0.00 −0.25 −0.25 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
MTl 0.00 −1.00 0.00 −1.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
MT2 0.00 0.00 −1.00 0.00 −1.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00