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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Gastroenterology. 2013 Aug 16;145(6):10.1053/j.gastro.2013.08.018. doi: 10.1053/j.gastro.2013.08.018

Figure 3. Essential role of COX2 in Kras-induced fibrosis and inflammation.

Figure 3

(A) Histology of COXKO/LSL/BAC mice treated with CD (COXKOBAC; n=5 and COXKO/LSL/BAC; n=5) and HFD (COXKOBAC; n=5 and COXKO/LSL/BAC; n=10) is shown. (B) Ras activity was measured through Raf-pull down assay comparing LSL/BAC animals to COXKO/LSL/BAC animals on CD and HFD.