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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: FEBS Lett. 2013 Sep 8;587(21):10.1016/j.febslet.2013.08.035. doi: 10.1016/j.febslet.2013.08.035

Figure 4. Inositol pyrophosphates do not regulate CDK5 activity.

Figure 4

Panel A describes the concentration-dependent inhibition of CDK5 activity by CDK5RAP1, measured as described in Section 2. In panel B the molar ratio of CDK5RAP1:CDK5 was 0.4:1. None of the added inositol phosphates (4 μM) affected CDK5 activity (p>0.05 vs vehicle control; analysis by ANOVA with a Dunnett's post hoc test, n=5-8). Further experiments (not shown) did not uncover “order-of-addition” effects upon CDK5 activity.