Table 1.

Top 10 GO categories “biological process” associated with genes differentially regulated by LIF treatment

GO process	GO-ID	p-value	Go	Ge	Gt
enzyme linked receptor protein signaling pathway	GO:0007167	8.58e-08	57	27.22	472
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	1.56e-07	41	17.07	296
prostate gland growth	GO:0060736	2.13e-07	7	0.58	10
phosphate metabolic process	GO:0006796	3.98e-07	117	74.45	1291
phosphorus metabolic process	GO:0006793	3.98e-07	117	74.45	1291
MAPKKK cascade	GO:0000165	4.31e-07	39	16.44	285
phosphorylation	GO:0016310	7.32e-07	104	64.82	1124
regulation of cellular component movement	GO:0051270	8.72e-07	34	13.73	238
regulation of MAPKKK cascade	GO:0043408	9.07e-07	26	8.99	156
regulation of phosphorus metabolic process	GO:0051174	9.46e-07	59	30.68	532

All associated GO-processes were ranked by their p-value. Go = Number of genes observed in the significantly regulated genes belonging to the respective biological process, Ge = Number of genes expected in the significantly regulated genes belonging to the respective biological process by a random pick of the same size, Gt = total number of genes belonging to the respective biological process.