Table 3.

Developmental Changes in Gene Expression in Shunt lambs Gene functional classification in 3-day Shunts

Functional classifications	Number of genes up-regulated	Number of genes down-regulated
cell cycle related genes	7	0
cell proliferation related genes	5	0
angiogenesis related genes	6	2
extracellular matrix and cell adhesion related genes	6	2
transcription factors	4	0
unclassified	90	15
total	118	19
Gene functional classification in 4-wk Shunts
Functional classifications	Number of genes up-regulated	Number of genes down-regulated
cell proliferation related genes	8	0
extracellular matrix related genes	3	28
angiogenesis related genes	0	6
specific cell signaling pathways	6	0
transcription factors	6	0
unclassified	132	62
total	155	96