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. 2013 Sep 15;36(1):83–103. doi: 10.1093/epirev/mxt008

Figure 2.

Figure 2.

Individual and pooled estimates of the association between hormone therapy use (any vs. minimal or no use) and Alzheimer's disease (AD) risk. “All AD, excluding clinical trial” excludes findings from Shumaker et al. (11). “All AD, studies with comprehensive dx” includes findings only from studies that evaluated all participants for dementia rather than relying on medical records. “AD plus dementia” adds the all-cause dementia findings from Ryan et al. (39) to all AD-specific findings. “Dementia plus AD” uses all all-cause dementia findings, substituting AD-specific findings from 7 studies that did not report results for all-cause dementia. For the study-specific estimates, the reference number is given in parentheses. CI, confidence interval; dx, diagnosis; HR, hazard ratio; OR, odds ratio. “All AD” includes all study-specific estimates shown below.