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. 2013 Dec 27;8(12):e82777. doi: 10.1371/journal.pone.0082777

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© 2013 Moncelet et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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U87 cells were incubated at 7*10⁴ cell/cm², with E-[c(RGDfK)2]-DOTA-Gd or MnCL₂ (400 µM during 4 h and 1 h, respectively). Applying a T₁-weighted sequence (T₁-w MRI), results with E-[c(RGDfK)2]-DOTA-Gd were significantly different from the unlabeled cells (★, p<0.05) and from the MnCl₂ condition (•, p<0.05).