Figure 3. Correlation of Keap1, Nrf2 with PPIA, Prdx6 and CD147 in human OSCC tissue array.
A, The expression of Keap1 had significant correlations with Nrf2 (P = 0.000, R = 0.549), and Prdx6 (P = 0.000, R = 0.735), and CD147 (P = 0.040, R = 0.268) by using the Pearson correlation coefficient test in human OSCC tissue array. B, The expression of Nrf2 was closely correlated with Keap1 (P = 0.000, R = 0.549) and Prdx6 (P = 0.000, R = 0.551) in human OSCC tissue array. C, Hierarchical Clustering of Keap1, Nrf2 with PPIA, Prdx6 and CD147 in human OSCC tissue array. Histoscore based on quantification using Aperio quantification software and statistics with Graph Pad Prism5. Mean ± SEM; 2-tailed Pearson correlation statistics.