Table 4. Association analysis of the clinicopathological parameters in relation to event-free survival of breast cancer patients (n=1005).

Parameter	No.	Noevent (%)	Log-rank P value	HR (95%CI)	P value	aHR (95%CI)*	P value*
age
≤50y	521	86 (16.51%)	0.173
>50y	484	67 (13.84%)		0.801 (0.582-1.103)	0.174	0.809 (0.582-1.126)	0.210
ER
positive	556	68 (12.23%)	0.153
negative	225	37 (16.44%)		1.342 (0.896-2.011)	0.154	1.468 (0.977-2.207)	0.065
PR
positive	511	57 (11.15%)	0.006
negative	266	48 (18.05%)		1.716 (1.167-2.524)	0.006	1.898 (1.287-2.798)	0.001
Her2
negative	576	68 (11.81%)	0.038
positive	202	37 (18.32%)		1.526 (1.020-2.281)	0.039	1.519 (1.016-2.271)	0.042
Lymoph node metastasis
negative	406	49 (12.07)	<0.0001
positive	279	82 (29.39%)		2.785 (1.953-3.973)	<0.0001	2.425 (1.686-3.486)	<0.0001
Size
<=2cm	338	31 (9.17%)	0.0008
>2cm	464	84 (18.10%)		1.998 (1.322-3.019)	0.001	1.913 (1.265-2.892)	0.002
Clinical stage
0-I	113	9 (7.96%)	0.004
II-IV	581	107 (18.42%)		2.590 (1.311-5.114)	0.006	2.278 (1.150-4.510)	0.018

^* Adjusted for age, BMI, age at menarche, age at first full-term pregnancy, menopause status, and family history of cancer in first-degree relatives.

Bold values indicate a statistical significance at 0.05 level.