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. 2013 Dec 27;8(12):e85053. doi: 10.1371/journal.pone.0085053

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© 2013 Sattayasai et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Cytotoxic effects of H₂O₂ on SK-N-SH cells after 24-h incubation. (B) Effects of ME on H₂O₂-induced cytotoxicity. (C) Cytotoxic effects of PCB-52 on SK-N-SH cells after 24-h incubation. (D) Effects of ME on PCB-52-induced cytotoxicity. SK-N-SH cells were preincubated with ME for 3 h before the treatment of H₂O₂ and PCB-52 for 24 h. Cell viability was determined by MTT assay and expressed as percentage compared to untreated cells. Data were reported as mean ± SEM (n=10 independent experiments for H₂O₂). *P < 0.05, ** P < 0.01, *** P < 0.001 compared to untreated control; ^# P < 0.05, ^### P < 0.001 compared to cells treated with corresponding chemicals concentration with no ME preincubation.