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. 2013 Dec 27;8(12):e85053. doi: 10.1371/journal.pone.0085053

Figure 5. Effects of ME on spatial memory in mice.

Figure 5

(A) Effects of ME on escape latency during 3 test trials of day1, 2 and 3 of the treatment using Morris water maze test. ME (50 or 100 mg/kg) or water (control) was orally administered to the mice 45 min before the trials (n=6). The escape latency (sec) was expressed as Mean ± SEM. * P < 0.05 compared to control in the same test trial on the same test day; # P <0.05 compared to the trial 1 of the same test condition in the same test day. (B) Effects of ME on time in right quadrant (probe trial) on day 1-3 and 14-16 of the treatment using Morris water maze test. The mice were orally administered with water (control) or ME (50 and 100 mg/kg) at 45 minutes before the test. The escape latency (sec) was expressed as Mean ± SEM (n=6). * P < 0.05 compared to control on the same test day; # P < 0.05 compared to 50 mg/kg ME-treated group on the same test day.