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Acute exposure to flow stimulates endocytosis of anti-PECAM/NCs in EC. (A, B) Effect of flow (1 dyn/cm2, 30 min) on endothelial binding (A) and internalization (B) of Ab/NC carrying 50, 100, and 200 Ab molecules per NC. (C) Acute exposure to flow regulates endocytosis of Ab/NC (50 Abs/NC) in a flow rate-dependent manner. Data are presented as mean ( SE (n = 8, *p < 0.05, **p < 0.01).
