Table 1.
Adoptively-transferred memory CD4 T cells |
Unprimed host | Memory CD4 T cell- mediated protection |
---|---|---|
Wild-type | Wild-type | +++++ |
B and T cell deficient (SCID) | ++ | |
B cell deficient (JHD) | +++ | |
T cell deficient (Nude) | +++ | |
IFNγ-deficient | Wild-type | +++++ |
B and T cell deficient (SCID) | − | |
B cell deficient (JHD) | +++ | |
T cell deficient (Nude) | +++ | |
Perforin-deficient | Wild-type | +++++ |
B and T cell deficient (SCID) | + | |
B cell deficient (JHD) | +++ | |
T cell deficient (Nude) | +++ |